CDKN1B-Y88 polyclonal, anti-human

CDKN1B-Y88 polyclonal, anti-human

€0.00
In stock
SKU
AC-AP20721b
Catalog Number: AC-AP20721b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB45062
Applications: WB
Datasheet

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Background:
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Other Names:
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1

Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 81-113 amino acids from human.

Gene Name: CDKN1B {ECO:0000303|PubMed:20824794}
Gene ID: 1027
Primary Accession: P46527
Other Accession: Q60439
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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