CDKN1C (clone 3E3), anti-human

CDKN1C (clone 3E3), anti-human

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In stock
SKU
BT-MCA3411
Catalog Number: BT-MCA3411
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s):
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Background:
The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.

Research Area: Cell Biology

Synonyms: BWS, WBS, p57, BWCR, KIP2, CDKN1C

Immunogen: Purified recombinant fragment of human CDKN1C expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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