CDKN1C monoclonal, anti-human
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In stock
SKU
AC-AM2072B
Catalog Number: AC-AM2072B
Size: 80 µl, 400 µl
Isotype: mouse IgM
Clone Name: 522CT9.5.1
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgM
Clone Name: 522CT9.5.1
Applications: WB
Datasheet
Request Information
Background:
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Other Names:
Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2
Target/Specificity:
This CDKN1C antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 34-64 amino acids from human CDKN1C.
Antigen Region:
34-64
Antigen Type: Synthetic Peptide
Gene Name: CDKN1C
Gene ID: 1028
Primary Accession: P49918
NCBI Accession: NP_000067.1;NP_001116102.1;NP_001116103.1
Other Accession: NP_000067.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Other Names:
Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2
Target/Specificity:
This CDKN1C antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 34-64 amino acids from human CDKN1C.
Antigen Region:
34-64
Antigen Type: Synthetic Peptide
Gene Name: CDKN1C
Gene ID: 1028
Primary Accession: P49918
NCBI Accession: NP_000067.1;NP_001116102.1;NP_001116103.1
Other Accession: NP_000067.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
| Is Featured? | No |
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