CDKN1C polyclonal, anti-mouse, rat

Background:
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

Synonyms: BWCR, BWS, KIP2, WBS, p57, p57Kip2

Cellular Location: Nucleus

Immunogen:
A synthetic peptide of human CDKN1C

Gene Symbol: CDKN1C

Gene ID: 1028

Swiss prot: P49918

Calculated MW: 32kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.