CDKN1C polyclonal (N-term), anti-human, mouse
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In stock
SKU
AC-AP10945A
Catalog Number: AC-AP10945A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19047
Applications: WB, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19047
Applications: WB, IF
Datasheet
Request Information
Background:
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Other Names:
Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2
Target/Specificity:
This CDKN1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-64 amino acids from the N-terminal region of human CDKN1C.
Antigen Region:
34-64
Antigen Type: Synthetic Peptide
Gene Name: CDKN1C
Gene ID: 1028
Primary Accession: P49918
NCBI Accession: NP_000067.1;NP_001116102.1;NP_001116103.1
Other Accession: NP_001116102.1;NP_000067.1;NP_001116103.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Other Names:
Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2
Target/Specificity:
This CDKN1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-64 amino acids from the N-terminal region of human CDKN1C.
Antigen Region:
34-64
Antigen Type: Synthetic Peptide
Gene Name: CDKN1C
Gene ID: 1028
Primary Accession: P49918
NCBI Accession: NP_000067.1;NP_001116102.1;NP_001116103.1
Other Accession: NP_001116102.1;NP_000067.1;NP_001116103.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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