CDT1 Polyclonal Antibody

Background:
The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
CDT 1, cdt1, CDT1, Chromatin licensing and DNA replication factor 1, DNA replication factor, DNA replication factor Cdt1, Double parked, Double parked Drosophila homolog of, Double parked homolog, DUP, Retroviral integration site 1, Retroviral integration site 2, Retroviral integration site1, Retroviral integration site2, RIS 2, RIS2

Immunogen: Synthetic peptide of human CDT1

Swissprot: Q9H211
Gene Accession: NP112190

Calculated MW: 60 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.