CDX1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6130a
Background:
CDX1 is a member of the caudal-type homeobox family of genes. These are cognates of the Drosophila caudal gene, which is required for anterior-posterior regional identity. Homologous genes have been found in mouse, rat, chicken, and Xenopus. The caudal-type homeobox genes are members of the hexapeptide (HEX) superclass, containing a conserved hexapeptide motif upstream of the homeodomain. Bonner et al. isolated the human CDX1 gene from a small intestine cDNA library using a murine Cdx1 cDNA probe. The nucleotide sequence of CDX1 was 81% identical to murine Cdx1 and predicted a 265-amino acid protein with 85% identity to the mouse protein. Northern analysis indicated that expression of CDX1 in adults appears to be limited to the intestine and colon. CDX1 plays a role in the terminal differentiation of the intestine.
Other Names:
Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6130a was selected from the C-term region of human CDX1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CDX1
Gene ID: 1044
Primary Accession: P47902
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CDX1 is a member of the caudal-type homeobox family of genes. These are cognates of the Drosophila caudal gene, which is required for anterior-posterior regional identity. Homologous genes have been found in mouse, rat, chicken, and Xenopus. The caudal-type homeobox genes are members of the hexapeptide (HEX) superclass, containing a conserved hexapeptide motif upstream of the homeodomain. Bonner et al. isolated the human CDX1 gene from a small intestine cDNA library using a murine Cdx1 cDNA probe. The nucleotide sequence of CDX1 was 81% identical to murine Cdx1 and predicted a 265-amino acid protein with 85% identity to the mouse protein. Northern analysis indicated that expression of CDX1 in adults appears to be limited to the intestine and colon. CDX1 plays a role in the terminal differentiation of the intestine.
Other Names:
Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6130a was selected from the C-term region of human CDX1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CDX1
Gene ID: 1044
Primary Accession: P47902
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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