CDX2 polyclonal, anti-human

Background:
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).

Other Names:
Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2, CDX2, CDX3

Antigen Types:
Synthetic Peptide

Gene Name:
CDX2
Gene ID:
1045
Primary Accession: Q99626
Other Accession: NP_001256;1045;12591 (mouse); 66019 (rat);