CEACAM polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP7364a
Catalog Number: AC-AP7364a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18886
Applications: WB, FC, IHC-P-Leica
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18886
Applications: WB, FC, IHC-P-Leica
Datasheet
Request Information
Background:
CEACAM is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. The protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
Other Names:
Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1, BGP-1, CD66a, CEACAM1, BGP, BGP1
Target/Specificity:
This CEACAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-77 amino acids from the N-terminal region of human CEACAM.
Antigen Region:
50-77
Antigen Type: Synthetic Peptide
Gene Name: CEACAM1 (HGNC:1814)
Gene ID: 634
Primary Accession: P13688
NCBI Accession: NP_001020083.1;NP_001171742.1;NP_001171744.1;NP_001171745.1;NP_001192273.1;NP_001703.2
Other Accession: P06731
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CEACAM is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. The protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
Other Names:
Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1, BGP-1, CD66a, CEACAM1, BGP, BGP1
Target/Specificity:
This CEACAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-77 amino acids from the N-terminal region of human CEACAM.
Antigen Region:
50-77
Antigen Type: Synthetic Peptide
Gene Name: CEACAM1 (HGNC:1814)
Gene ID: 634
Primary Accession: P13688
NCBI Accession: NP_001020083.1;NP_001171742.1;NP_001171744.1;NP_001171745.1;NP_001192273.1;NP_001703.2
Other Accession: P06731
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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