CD66c (CEACAM6) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60595
Background:
The CD66 (carcinoembryonic antigen, CEA, Biliary glycoprotein I, BGP-1, CECAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues . CD66 mRNA is strongly expressed in primary colon tumors and, to a lesser extent, in normal colonic tissue . The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2. . CD66a, CD66b, CD66c, CD66d, CD66e and CD66f are the best characterized CD66 antigens, and CD66a-d expression upregulates on the surface of granulocytes upon stimulation . CD66 isoforms mediate homotypic and heterotypic intercellular adhesion events independently of cell type .
Alternative Name:
Carcinoembryonic antigen-related cell, adhesion molecule 6, Non-specific crossreacting antigen, Normal cross-reacting antigen, CD66c, CEACAM6, NCA
Application Dilution: WB: 1:500~1:1000
Specificity: CEACAM6 polyclonal antibody detects endogenous levels of CEACAM6 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CEACAM6
MW: ~ 37 kDa
Swis Prot.: P40199
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The CD66 (carcinoembryonic antigen, CEA, Biliary glycoprotein I, BGP-1, CECAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues . CD66 mRNA is strongly expressed in primary colon tumors and, to a lesser extent, in normal colonic tissue . The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2. . CD66a, CD66b, CD66c, CD66d, CD66e and CD66f are the best characterized CD66 antigens, and CD66a-d expression upregulates on the surface of granulocytes upon stimulation . CD66 isoforms mediate homotypic and heterotypic intercellular adhesion events independently of cell type .
Alternative Name:
Carcinoembryonic antigen-related cell, adhesion molecule 6, Non-specific crossreacting antigen, Normal cross-reacting antigen, CD66c, CEACAM6, NCA
Application Dilution: WB: 1:500~1:1000
Specificity: CEACAM6 polyclonal antibody detects endogenous levels of CEACAM6 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CEACAM6
MW: ~ 37 kDa
Swis Prot.: P40199
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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