CEACAM7 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP17149C
Catalog Number: AC-AP17149C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35958
Applications: IHC-P, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35958
Applications: IHC-P, WB
Datasheet
Request Information
Background:
CEA-related cell adhesion molecule 7 (CEACAM7,CGM2) belongs to the carcinoembryonic antigen (CEA) family. It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts. CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constantlike A domain.
Other Names:
Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2, CEACAM7, CGM2
Target/Specificity:
This CEACAM7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids from the Central region of human CEACAM7.
Antigen Region:
112-140
Antigen Type: Synthetic Peptide
Gene Name: CEACAM7 (HGNC:1819)
Gene ID: 1087
Primary Accession: Q14002
NCBI Accession: NP_008821.1
Other Accession: NP_008821.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CEA-related cell adhesion molecule 7 (CEACAM7,CGM2) belongs to the carcinoembryonic antigen (CEA) family. It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts. CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constantlike A domain.
Other Names:
Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2, CEACAM7, CGM2
Target/Specificity:
This CEACAM7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids from the Central region of human CEACAM7.
Antigen Region:
112-140
Antigen Type: Synthetic Peptide
Gene Name: CEACAM7 (HGNC:1819)
Gene ID: 1087
Primary Accession: Q14002
NCBI Accession: NP_008821.1
Other Accession: NP_008821.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review