CEBPA polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

Synonyms: CEBP, C/EBP-alpha

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human CEBPA

Gene Symbol: CEBPA

Gene ID: 1050

Swiss prot: P49715

Calculated MW: 38kDa/36kDa/26kDa/41kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.