CEBPB (clone 3H9), anti-human

Background:
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: LAP, CRP2, TCF5, IL6DBP, NF-IL6, MGC32080, C/EBP-beta

Immunogen: Purified recombinant fragment of human CEBPB expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage