CENPA Antibody (Center) Blocking peptide

CENPA Antibody (Center) Blocking peptide

€363.00
In stock
SKU
AC-BP13843c
Catalog Number: AC-BP13843c
Size: 500 µg
Datasheet
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Background:
Centromeres are the differentiated chromosomal domainsthat specify the mitotic behavior of chromosomes. CENPA encodes acentromere protein which contains a histone H3 related histone folddomain that is required for targeting to the centromere. CENPA isproposed to be a component of a modified nucleosome ornucleosome-like structure in which it replaces 1 or both copies ofconventional histone H3 in the (H3-H4)2 tetrameric core of thenucleosome particle. Alternative splicing results in multipletranscript variants encoding distinct isoforms. [provided byRefSeq].

Other Names:
Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A, CENPA

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13843c was selected from the Center region of CENPA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: CENPA

Gene ID: 1058
Primary Accession: P49450
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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