CENPA antibody (clone 1D4-1A3), anti-human
€435.00
In stock
SKU
AC-AT1493a
Catalog Number: AC-AT1493a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT1493a">Request Information
Background:
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Other Names:
Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A, CENPA
Antigen Type:
Recombinant Protein
Gene Name: CENPA
Gene ID: 1058
NCBI Accession: NP_001035891.1;NP_001800.1
Primary Accession: P49450
Other Accession: BC000881
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Other Names:
Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A, CENPA
Antigen Type:
Recombinant Protein
Gene Name: CENPA
Gene ID: 1058
NCBI Accession: NP_001035891.1;NP_001800.1
Primary Accession: P49450
Other Accession: BC000881
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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