CENPA polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP13843c
Catalog Number: AC-AP13843c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33757
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33757
Applications: WB
Datasheet
Request Information
Background:
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
Other Names:
Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A, CENPA
Target/Specificity:
This CENPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the Central region of human CENPA.
Antigen Region:
82-110
Antigen Type: Synthetic Peptide
Gene Name: CENPA
Gene ID: 1058
Primary Accession: P49450
NCBI Accession: NP_001035891.1;NP_001800.1
Other Accession: Q8R565; P49449; NP_001800.1; NP_001035891.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
Other Names:
Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A, CENPA
Target/Specificity:
This CENPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the Central region of human CENPA.
Antigen Region:
82-110
Antigen Type: Synthetic Peptide
Gene Name: CENPA
Gene ID: 1058
Primary Accession: P49450
NCBI Accession: NP_001035891.1;NP_001800.1
Other Accession: Q8R565; P49449; NP_001800.1; NP_001035891.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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