CENPC polyclonal, anti-human

Background:
Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.

Synonyms: MIF2, hcp-4, CENP-C, CENPC1

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human CENPC

Gene Symbol: CENPC

Gene ID: 1060

Swiss prot: Q03188

Calculated MW: 107kDa

Recommended dilution:
IHC 1:20-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.