CENPJ antibody (clone 5D5), anti-human

CENPJ antibody (clone 5D5), anti-human

€435.00
In stock
SKU
AC-AT1494a
Catalog Number: AC-AT1494a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
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Background:
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

Other Names:
Centromere protein J, CENP-J, Centrosomal P41-associated protein, LAG-3-associated protein, LYST-interacting protein 1, CENPJ, CPAP, LAP, LIP1

Antigen Type:
Recombinant Protein

Gene Name: CENPJ
Gene ID: 55835
NCBI Accession: NP_060921.3
Primary Accession: Q9HC77
Other Accession: NM_018451
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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