CDC46 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP68995
Catalog Number: AC-AP51079
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, E
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, E
Datasheet
Request Information
Background:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
Other Names:
MCM5; CDC46; DNA replication licensing factor MCM5; CDC46 homolog; P1-CDC46
Antigen Type: synthetic peptide
Antigen Type: MCM5
Gene ID: 4174
Primary Accession: P33992
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
Other Names:
MCM5; CDC46; DNA replication licensing factor MCM5; CDC46 homolog; P1-CDC46
Antigen Type: synthetic peptide
Antigen Type: MCM5
Gene ID: 4174
Primary Accession: P33992
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