CEP55 polyclonal, anti-human
€305.00
In stock
SKU
BS61640
Background:
CEP55 (centrosomal protein of 55 kDa), also known as URCC6 (up-regulated in colon cancer 6), is a 464 amino acid protein that localizes to the centrosome during interphase and may be found throughout the cell during mitosis. Widely expressed with highest expression in testis and lower expression in thymus, bone marrow, placenta, fetal heart, digestive tract and several carcinomas, CEP55 exists as a homodimer that interacts with centrosome components and is involved in mitotic exit and cytokinesis. Human CEP55 undergoes several phosphorylation events throughout the cell cycle, most of which are necessary for proper CEP55 function. Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression. Two isoforms of CEP55 are expressed due to alternative splicing events.
Alternative Name:
Centrosomal protein of 55 kDa, Cep55, Up-regulated in colon cancer 6, CEP55, C10orf3, URCC6
Application Dilution: WB: 1:500~1:1000
Specificity: CEP55 polyclonal antibody detects endogenous levels of CEP55 protein.
Immunogen:
Synthetic peptide, corresponding Human CEP55.
MW: ~ 55 kDa
Swis Prot.: Q53EZ4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
CEP55 (centrosomal protein of 55 kDa), also known as URCC6 (up-regulated in colon cancer 6), is a 464 amino acid protein that localizes to the centrosome during interphase and may be found throughout the cell during mitosis. Widely expressed with highest expression in testis and lower expression in thymus, bone marrow, placenta, fetal heart, digestive tract and several carcinomas, CEP55 exists as a homodimer that interacts with centrosome components and is involved in mitotic exit and cytokinesis. Human CEP55 undergoes several phosphorylation events throughout the cell cycle, most of which are necessary for proper CEP55 function. Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression. Two isoforms of CEP55 are expressed due to alternative splicing events.
Alternative Name:
Centrosomal protein of 55 kDa, Cep55, Up-regulated in colon cancer 6, CEP55, C10orf3, URCC6
Application Dilution: WB: 1:500~1:1000
Specificity: CEP55 polyclonal antibody detects endogenous levels of CEP55 protein.
Immunogen:
Synthetic peptide, corresponding Human CEP55.
MW: ~ 55 kDa
Swis Prot.: Q53EZ4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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