Cerebellin Peptide
€205.00
In stock
SKU
350125
Protein Family: Hormones
Pathway and Disease: Endocrine System, Nervous and Sensory Systems, Signaling Molecules and Interaction
Alternate Names: Cerebellin; Cerebellin-1; precerebellin; CER; CBLN1
Accession No.: P23435
Description:
Cerebellin is a 16-amino acid peptide originally isolated from rat cerebellum, which actually comes from precerebellin (cerebellin-1) processing into cerebellin and [des-Ser1]-cerebellin. Cerebellin is widely distributed in the central nervous system, where it exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release.
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 1632.81 g/mol
Sequence:
Human: H-Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His-OH or H-SGSAKVAFSAIRSTNH-OH
Composition:
C69H113N23O23
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Pathway and Disease: Endocrine System, Nervous and Sensory Systems, Signaling Molecules and Interaction
Alternate Names: Cerebellin; Cerebellin-1; precerebellin; CER; CBLN1
Accession No.: P23435
Description:
Cerebellin is a 16-amino acid peptide originally isolated from rat cerebellum, which actually comes from precerebellin (cerebellin-1) processing into cerebellin and [des-Ser1]-cerebellin. Cerebellin is widely distributed in the central nervous system, where it exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release.
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 1632.81 g/mol
Sequence:
Human: H-Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His-OH or H-SGSAKVAFSAIRSTNH-OH
Composition:
C69H113N23O23
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
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