CERK Polyclonal Antibody

Background:
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.

Research Area: Cell Biology

Synonyms:
Acylsphingosine kinase, Ceramide kinase, Cerk, CERK1, dA59H18.2, dA59H18.3, hCERK, KIAA1646, Lipid kinase 4, Lipid kinase LK4, LK4

Immunogen: Recombinant protein of human CERK

Swissprot: Q8TCT0
Gene Accession: BC126940

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-79406/sc-79409/sc-98700