CES2 Polyclonal Antibody

Background:
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.

Research Area: Metabolism, Signal Transduction

Synonyms:
Carboxylesterase 2 (intestine, liver), Carboxylesterase 2, CE-2, CES2, CES2A1, Cocaine esterase, EC 3.1.1.1, EST2, hCE-2, ICE, Iintestinal carboxylesterase liver carboxylesterase 2, Intestinal carboxylesterase, liver carboxylesterase-2, Methylumbelliferyl acetate deacetylase 2, PCE 2, PCE-2

Immunogen: Synthetic peptide of human CES2

Swissprot: O00748
Gene Accession: NP003860

Calculated MW: 62 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.