CETN2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7766
Background:
The EF-hand type Ca2+-binding proteins family consists of several members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.
Alternative Name:
20kD calcium binding protein, CALT, caltractin, Caltractin isoform 1, CEN2, centrin, centrin, EF hand protein, 2, Centrin-2, Centrin2, CETN2, CETN2_HUMAN, EF hand protein 2, EF-hand protein,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: CETN2 polyclonal antibody detects endogenous levels of CETN2 protein.
Immunogen:
Recombinant full length Human CETN2.
MW: ~ 20 kDa
Swis Prot.: P41208
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The EF-hand type Ca2+-binding proteins family consists of several members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.
Alternative Name:
20kD calcium binding protein, CALT, caltractin, Caltractin isoform 1, CEN2, centrin, centrin, EF hand protein, 2, Centrin-2, Centrin2, CETN2, CETN2_HUMAN, EF hand protein 2, EF-hand protein,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: CETN2 polyclonal antibody detects endogenous levels of CETN2 protein.
Immunogen:
Recombinant full length Human CETN2.
MW: ~ 20 kDa
Swis Prot.: P41208
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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