Cezf Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1972b
Background:
CEZF bears substantial homology to the zinc finger and leucine zipper motifs of the human gene products AF10, MLLT6, and BR140. The functional domain of the zing finger motif, which is structurally different from previously described zinc finger motifs, is potentially disrupted in leukemia-associated chromosomal translocations. This zinc finger motif present in CEZF, called the leukemia-associatged protein (LAP) finger, is an important DNA-binding domain in this group of regulatory proteins, and may be involved in leukemogenesis.
Other Names:
Uncharacterized protein F54F22, isoform a, F54F22/F54F23/F54F24
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1972b was selected from the C-term region of human Cezf. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: zfp-1 {ECO:0000312|WormBase:F54F2.2a}
Gene ID: 176237
Primary Accession: P34447
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CEZF bears substantial homology to the zinc finger and leucine zipper motifs of the human gene products AF10, MLLT6, and BR140. The functional domain of the zing finger motif, which is structurally different from previously described zinc finger motifs, is potentially disrupted in leukemia-associated chromosomal translocations. This zinc finger motif present in CEZF, called the leukemia-associatged protein (LAP) finger, is an important DNA-binding domain in this group of regulatory proteins, and may be involved in leukemogenesis.
Other Names:
Uncharacterized protein F54F22, isoform a, F54F22/F54F23/F54F24
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1972b was selected from the C-term region of human Cezf. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: zfp-1 {ECO:0000312|WormBase:F54F2.2a}
Gene ID: 176237
Primary Accession: P34447
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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