CFD polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60563
Background:
Adipsin is the mouse homolog of the previously described human complement Factor D, a serine protease, which is now designated human Adipsin. Human Adipsin is highly expressed in and secreted by adipose tissue, and it has also been found in monocytes and macrophages. Rodent Adipsin has only been detected in high levels in adipose tissue. It has been shown that complement factor B, when complexed with activated complement component C3, is cleaved by Adipsin. While low expression of Adipsin has been confirmed in obese mice with hypothalamic defects, this inverse correlation between Adipsin expression and obesity has not been demonstrated in humans.
Alternative Name:
Complement factor D, Adipsin, C3 convertase activator, Properdin factor D, CFD, DF, PFD
Application Dilution: WB: 1:500~1:1000
Specificity: CFD polyclonal antibody detects endogenous levels of CFD protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CFD
MW: ~ 27 kDa
Swis Prot.: P00746
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Adipsin is the mouse homolog of the previously described human complement Factor D, a serine protease, which is now designated human Adipsin. Human Adipsin is highly expressed in and secreted by adipose tissue, and it has also been found in monocytes and macrophages. Rodent Adipsin has only been detected in high levels in adipose tissue. It has been shown that complement factor B, when complexed with activated complement component C3, is cleaved by Adipsin. While low expression of Adipsin has been confirmed in obese mice with hypothalamic defects, this inverse correlation between Adipsin expression and obesity has not been demonstrated in humans.
Alternative Name:
Complement factor D, Adipsin, C3 convertase activator, Properdin factor D, CFD, DF, PFD
Application Dilution: WB: 1:500~1:1000
Specificity: CFD polyclonal antibody detects endogenous levels of CFD protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CFD
MW: ~ 27 kDa
Swis Prot.: P00746
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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