CFH polyclonal (Center), anti-human
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In stock
SKU
AC-AP10942c
Catalog Number: AC-AP10942c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18698
Applications: IHC-P, WB, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18698
Applications: IHC-P, WB, IF
Datasheet
Request Information
Background:
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
Complement factor H, H factor 1, CFH, HF, HF1, HF2
Target/Specificity:
This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids of human CFH.
Antigen Region:
751-780
Antigen Type: Synthetic Peptide
Gene Name: CFH
Gene ID: 3075
Primary Accession: P08603
NCBI Accession: NP_000177.2
Other Accession: NP_000177.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
Complement factor H, H factor 1, CFH, HF, HF1, HF2
Target/Specificity:
This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids of human CFH.
Antigen Region:
751-780
Antigen Type: Synthetic Peptide
Gene Name: CFH
Gene ID: 3075
Primary Accession: P08603
NCBI Accession: NP_000177.2
Other Accession: NP_000177.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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