CFHR1 Polyclonal Antibody

Background:
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Research Area: Cardiovascular, Immunology

Synonyms:
CFHL, CFHL1, CFHL1P, CFHR1, CFHR1P, Complement factor H related 1, Complement factor H related 1 pseudogene, Complement factor H related protein 1 precursor, Complement factor H-related protein 1, FHR 1, FHR-1, FHR1, FHR1, H factor (complement) like 1, H factor (complement) like 2, H factor like protein 1, H factor-like protein 1, H-factor-like 1, H36 1, H36 2, H36, HFL1, HFL2, MGC104329

Immunogen: Recombinant protein of human CFHR1

Swissprot: Q03591
Gene Accession: BC016755

Calculated MW: 38 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-17953