CFL2 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP14117a
Background:
This gene encodes an intracellular protein that isinvolved in the regulation of actin-filament dynamics. This proteinis a major component of intranuclear and cytoplasmic actin rods. Itcan bind G- and F-actin in a 1:1 ratio of cofilin to actin, and itreversibly controls actin polymerization and depolymerization in apH-dependent manner. Mutations in this gene cause nemaline myopathytype 7, a form of congenital myopathy. Alternative splicing resultsin multiple transcript variants.
Other Names:
Cofilin-2, Cofilin, muscle isoform, CFL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14117a was selected from the N-term region of CFL2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CFL2
Gene ID: 1073
Primary Accession: Q9Y281
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes an intracellular protein that isinvolved in the regulation of actin-filament dynamics. This proteinis a major component of intranuclear and cytoplasmic actin rods. Itcan bind G- and F-actin in a 1:1 ratio of cofilin to actin, and itreversibly controls actin polymerization and depolymerization in apH-dependent manner. Mutations in this gene cause nemaline myopathytype 7, a form of congenital myopathy. Alternative splicing resultsin multiple transcript variants.
Other Names:
Cofilin-2, Cofilin, muscle isoform, CFL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14117a was selected from the N-term region of CFL2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CFL2
Gene ID: 1073
Primary Accession: Q9Y281
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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