CGGBP1 Polyclonal Antibody

Background:
This gene encodes a CGG repeat-binding protein that primarily localizes to the nucleus. CGG trinucleotide repeats are implicated in many disorders as they often act as transcription- and translation-regulatory elements, can produce hairpin structures which cause DNA replication errors, and form regions prone to chromosomal breakage. CGG repeats are also targets for CpG methylation. In addition to its ability to bind CGG repeats and regulate transcription, this gene is believed to play a role in DNA damage repair and telomere protection. In vitro studies indicate this protein does not bind to methylated CpG sequences.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
CGGBP1, CGGBP, p20-CGGBP

Immunogen: Recombinant fusion protein of human CGGBP1 (NP_003654.3).

Swissprot: Q9UFW8
Gene ID: 8545

Calculated MW: 18 kDa
Observed MW: 20 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.