Pragmin (phospho Tyr413) polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP67168
Background:
Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth (By similarity). Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism (By similarity). Acts as a critical coactivator of Notch signaling (By similarity).
Other Names:
SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223
Antigen Type: synthetic peptide
Antigen Type: PRAG1 (HGNC:25438)
Gene ID: 157285
Primary Accession: Q86YV5
Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth (By similarity). Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism (By similarity). Acts as a critical coactivator of Notch signaling (By similarity).
Other Names:
SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223
Antigen Type: synthetic peptide
Antigen Type: PRAG1 (HGNC:25438)
Gene ID: 157285
Primary Accession: Q86YV5
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