CHAT Polyclonal Antibody

Background:
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. 

Research Area: Cancer, Neuroscience

Synonyms:
Acetyl CoA choline O acetyltransferase, Acetyl CoA:choline O acetyltransferase, Chat, CHOACTase, Choline acetylase, choline acetyltransferase, Choline O acetyltransferase, Choline O-acetyltransferase, CLAT, CMS1A, CMS1A2, EC 2.3.1.6, OTTHUMP00000019583, OTTHUMP00000019584

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CHAT

Swissprot: P28329,Q03059,P32738

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 350 μg/mL
Dilution: IHC 1:100-1:500

Storage:
Store at -20°C. Avoid freeze / thaw cycles.