CHCHD3 Polyclonal Antibody

Background:
The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Metabolism, Signal transduction, Tags & Cell Markers

Synonyms:
CHCH3, CHCHD 3, Chchd3, Coiled coil helix coiled coil helix domain containing 3, Coiled coil helix coiled coil helix domain containing protein 3 mitochondrial, Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, FLJ20420, MINOS3, mitochondrial, Mitochondrial inner membrane organizing system 3, PPP1R22, Protein phosphatase 1 regulatory subunit 22

Immunogen: Full length fusion protein

Swissprot: Q9NX63
Gene Accession: BC011596

Calculated MW: 26 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.