CHD1L polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP16423c
Catalog Number: AC-AP16423c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35858
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35858
Applications: WB
Datasheet
Request Information
Background:
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM].
Other Names:
Chromodomain-helicase-DNA-binding protein 1-like, Amplified in liver cancer protein 1, CHD1L, ALC1
Target/Specificity:
This CHD1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-590 amino acids from the Central region of human CHD1L.
Antigen Region:
561-590
Antigen Type: Synthetic Peptide
Gene Name: CHD1L {ECO:0000303|PubMed:34210977, ECO:0000312|HGNC:HGNC:1916}
Gene ID: 9557
Primary Accession: Q86WJ1
NCBI Accession: NP_001243265.1;NP_001243266.1;NP_001243267.1;NP_004275.4;NP_078844.2
Other Accession: NP_004275.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM].
Other Names:
Chromodomain-helicase-DNA-binding protein 1-like, Amplified in liver cancer protein 1, CHD1L, ALC1
Target/Specificity:
This CHD1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-590 amino acids from the Central region of human CHD1L.
Antigen Region:
561-590
Antigen Type: Synthetic Peptide
Gene Name: CHD1L {ECO:0000303|PubMed:34210977, ECO:0000312|HGNC:HGNC:1916}
Gene ID: 9557
Primary Accession: Q86WJ1
NCBI Accession: NP_001243265.1;NP_001243266.1;NP_001243267.1;NP_004275.4;NP_078844.2
Other Accession: NP_004275.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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