CHD3 antibody (clone 5.0E+12), anti-human
€435.00
In stock
SKU
AC-AT1513a
Catalog Number: AC-AT1513a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC
Request Information AC-AT1513a">Request Information
Background:
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Other Names:
Chromodomain-helicase-DNA-binding protein 3, CHD-3, ATP-dependent helicase CHD3, Mi-2 autoantigen 240 kDa protein, Mi2-alpha, Zinc finger helicase, hZFH, CHD3
Antigen Type:
Recombinant Protein
Gene Name: CHD3
Gene ID: 1107
NCBI Accession: NP_001005271.2;NP_001005273.1;NP_005843.2
Primary Accession: Q12873
Other Accession: NM_001005273
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Other Names:
Chromodomain-helicase-DNA-binding protein 3, CHD-3, ATP-dependent helicase CHD3, Mi-2 autoantigen 240 kDa protein, Mi2-alpha, Zinc finger helicase, hZFH, CHD3
Antigen Type:
Recombinant Protein
Gene Name: CHD3
Gene ID: 1107
NCBI Accession: NP_001005271.2;NP_001005273.1;NP_005843.2
Primary Accession: Q12873
Other Accession: NM_001005273
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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