CHD4 polyclonal, anti-human

Background:
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: CHD-4, Mi-2b, Mi2-BETA, SIHIWES

Cellular Location: Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center

Immunogen:
Recombinant protein of human CHD4

Gene Symbol: CHD4

Gene ID: 1108

Swiss prot: Q14839

Calculated MW: 218kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.