CHERP polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60123
Background:
The regulation of the intracellular concentration of calcium is important for proper maintenance of voltage-gated ion channels which control muscle and nerve function. Calcium homeostasis is regulated by a variety of proteins. CHERP (calcium homeostasis endoplasmic reticulum protein), also known as SRA1, DAN16 or SCAF6, is a 916 amino acid protein that localizes to the cytoplasm and the endoplasmic reticulum (ER). Expressed in pancreas, brain, lung, placenta, liver, kidney, heart and skeletal muscle, CHERP is involved in maintaining calcium homeostasis and plays a role in cell growth and proliferation. CHERP contains one G-patch domain, one RPR domain and one SURP motif and is expressed as two isoforms due to alternative splicing events.
Alternative Name:
Calcium homeostasis endoplasmic reticulum protein, ERPROT 213-21, SR-related CTD-associated factor 6, DAN26, SCAF6
Application Dilution: WB: 1:500~1:1000
Specificity: CHERP polyclonal antibody detects endogenous levels of CHERP protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CHERP.
MW: ~ 104 kDa
Swis Prot.: Q8IWX8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The regulation of the intracellular concentration of calcium is important for proper maintenance of voltage-gated ion channels which control muscle and nerve function. Calcium homeostasis is regulated by a variety of proteins. CHERP (calcium homeostasis endoplasmic reticulum protein), also known as SRA1, DAN16 or SCAF6, is a 916 amino acid protein that localizes to the cytoplasm and the endoplasmic reticulum (ER). Expressed in pancreas, brain, lung, placenta, liver, kidney, heart and skeletal muscle, CHERP is involved in maintaining calcium homeostasis and plays a role in cell growth and proliferation. CHERP contains one G-patch domain, one RPR domain and one SURP motif and is expressed as two isoforms due to alternative splicing events.
Alternative Name:
Calcium homeostasis endoplasmic reticulum protein, ERPROT 213-21, SR-related CTD-associated factor 6, DAN26, SCAF6
Application Dilution: WB: 1:500~1:1000
Specificity: CHERP polyclonal antibody detects endogenous levels of CHERP protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CHERP.
MW: ~ 104 kDa
Swis Prot.: Q8IWX8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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