CHIT1 (clone 1D9G2), anti-human

Background:
CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

Research Area: Immunology

Synonyms: Chitotriosidase, CHI3, CHIT, FLJ00314, MGC125322, CHIT1

Immunogen: Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage