Chk2 polyclonal, anti-human, mouse, rat antibody
€295.00
In stock
SKU
AC-ABV10231-100
Catalog Number: AC-ABV10231-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IF
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IF
Datasheet
Request Information
Background:
Chk2 is the mammalian homologue of yeast Cds1/Rad53. In response to DNA damage, a checkpoint kinase ATM phosphorylates and activates Chk2, which in turn phosphorylates and activates p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is mutated in breast and ovarian cancer.
Other Names:
CHEK2 , CHK2 , CDS1 , RAD53 , LFS2 , HuCds1, PP1425, OTTHUMP00000028871
Primary Accession: O96017
Gene Name: CHEK2
Gene ID: 11200
Concentration (mg/ml): 0.5 mg/ml
Chk2 is the mammalian homologue of yeast Cds1/Rad53. In response to DNA damage, a checkpoint kinase ATM phosphorylates and activates Chk2, which in turn phosphorylates and activates p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is mutated in breast and ovarian cancer.
Other Names:
CHEK2 , CHK2 , CDS1 , RAD53 , LFS2 , HuCds1, PP1425, OTTHUMP00000028871
Primary Accession: O96017
Gene Name: CHEK2
Gene ID: 11200
Concentration (mg/ml): 0.5 mg/ml
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