CHMP2A polyclonal, anti-human

Background:
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).

Synonyms: BC-2, BC2, CHMP2, VPS2, VPS2A

Cellular Location: Cytoplasmic side Late endosome membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human CHMP2A

Gene Symbol: CHMP2A

Gene ID: 27243

Swiss prot: O43633

Calculated MW: 25kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.