CHMP2B antibody (clone M1), anti-human
€435.00
In stock
SKU
AC-AT1522a
Catalog Number: AC-AT1522a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT1522a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT1522a">Request Information
Background:
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Other Names:
Charged multivesicular body protein 2b, CHMP25, Chromatin-modifying protein 2b, CHMP2b, Vacuolar protein sorting-associated protein 2-2, Vps2-2, hVps2-2, CHMP2B
Antigen Type:
Recombinant Protein
Gene Name: CHMP2B
Gene ID: 25978
NCBI Accession: NP_001231573.1;NP_054762.2
Primary Accession: Q9UQN3
Other Accession: BC001553.1
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Other Names:
Charged multivesicular body protein 2b, CHMP25, Chromatin-modifying protein 2b, CHMP2b, Vacuolar protein sorting-associated protein 2-2, Vps2-2, hVps2-2, CHMP2B
Antigen Type:
Recombinant Protein
Gene Name: CHMP2B
Gene ID: 25978
NCBI Accession: NP_001231573.1;NP_054762.2
Primary Accession: Q9UQN3
Other Accession: BC001553.1
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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