CHMP2B Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13303a
Background:
This gene encodes a component of the heteromeric ESCRT-IIIcomplex (Endosomal Sorting Complex Required for Transport III) thatfunctions in the recycling or degradation of cell surfacereceptors. ESCRT-III functions in the concentration andinvagination of ubiquitinated endosomal cargos into intralumenalvesicles. The protein encoded by this gene is found as a monomer inthe cytosol or as an oligomer in ESCRT-III complexes on endosomalmembranes. It is expressed in neurons of all major regions of thebrain. Mutations in this gene result in one form of familialfrontotemporal lobar degeneration.
Other Names:
Charged multivesicular body protein 2b, CHMP25, Chromatin-modifying protein 2b, CHMP2b, Vacuolar protein sorting-associated protein 2-2, Vps2-2, hVps2-2, CHMP2B
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13303a was selected from the N-term region of CHMP2B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CHMP2B
Gene ID: 25978
Primary Accession: Q9UQN3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a component of the heteromeric ESCRT-IIIcomplex (Endosomal Sorting Complex Required for Transport III) thatfunctions in the recycling or degradation of cell surfacereceptors. ESCRT-III functions in the concentration andinvagination of ubiquitinated endosomal cargos into intralumenalvesicles. The protein encoded by this gene is found as a monomer inthe cytosol or as an oligomer in ESCRT-III complexes on endosomalmembranes. It is expressed in neurons of all major regions of thebrain. Mutations in this gene result in one form of familialfrontotemporal lobar degeneration.
Other Names:
Charged multivesicular body protein 2b, CHMP25, Chromatin-modifying protein 2b, CHMP2b, Vacuolar protein sorting-associated protein 2-2, Vps2-2, hVps2-2, CHMP2B
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13303a was selected from the N-term region of CHMP2B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CHMP2B
Gene ID: 25978
Primary Accession: Q9UQN3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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