CHP1 Polyclonal Antibody

Background:
This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity.CHP1 (Calcineurin Like EF-Hand Protein 1) is a Protein Coding gene. Among its related pathways are Role of Calcineurin-dependent NFAT signaling in lymphocytes and Calcineurin-regulated NFAT-dependent transcription in lymphocytes. GO annotations related to this gene include calcium ion binding and microtubule binding. An important paralog of this gene is CHP2.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Calcineurin B homolog, Calcineurin B homologous protein, Calcineurin homologous protein, Calcineurin like EF hand protein 1, Calcium binding protein CHP, Calcium binding protein p22, Calcium-binding protein CHP, Calcium-binding protein p22, chp, CHP1, Sid 470, Sid470, SLC9A1 binding protein, SLC9A1BP, Wrch2

Immunogen: Synthetic peptide of human CHP1

Swissprot: Q99653
Gene Accession: NP009167

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.66 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.