CHRM1 polyclonal, anti-human, mouse, rat

Background:
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13

Synonyms: M1, HM1, M1R

Cellular Location: Membrane

Immunogen:
Recombinant protein of human CHRM1

Gene Symbol: CHRM1

Gene ID: 1128

Swiss prot: P11229

Calculated MW: 51kDa

Recommended dilution:
WB 1:200-1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.