CHRM4 polyclonal, anti-human, mouse, rat

Background:
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition.

Synonyms: HM4, M4R

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human CHRM4

Gene Symbol: CHRM4

Gene ID: 1132

Swiss prot: P08173

Calculated MW: 53kDa

Recommended dilution:
IHC 1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.