CHRNA10 polyclonal, anti-human

Background:
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Synonyms: CHRNA10

Cellular Location: Cell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse

Immunogen:
Recombinant Protein of human CHRNA10

Gene Symbol: CHRNA10

Gene ID: 57053

Swiss prot: Q9GZZ6

Calculated MW: 50kDa

Recommended dilution:
WB 1:200-1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.