CHRNA3 polyclonal, anti-human, mouse, rat

Background:
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

Synonyms: LNCR2, PAOD2, NACHRA3

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human CHRNA3

Gene Symbol: CHRNA3

Gene ID: 1136

Swiss prot: P32297

Calculated MW: 55 kDa

Recommended dilution:
WB 1:1000-5000, IHC 1:15-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.