CHRNA3 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP5022A
Catalog Number: AC-AP5022A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB25608
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB25608
Applications: IHC-P, WB
Datasheet
Request Information
Background:
CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
Other Names:
Neuronal acetylcholine receptor subunit alpha-3, CHRNA3, NACHRA3
Target/Specificity:
This CHRNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human CHRNA3.
Antigen Region:
25-52
Antigen Type: Synthetic Peptide
Gene Name: CHRNA3
Gene ID: 1136
Primary Accession: P32297
NCBI Accession: NP_000734.2;NP_001160166.1
Other Accession: Q07263
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
Other Names:
Neuronal acetylcholine receptor subunit alpha-3, CHRNA3, NACHRA3
Target/Specificity:
This CHRNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human CHRNA3.
Antigen Region:
25-52
Antigen Type: Synthetic Peptide
Gene Name: CHRNA3
Gene ID: 1136
Primary Accession: P32297
NCBI Accession: NP_000734.2;NP_001160166.1
Other Accession: Q07263
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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