CHRNA4 polyclonal, anti-human

Background:
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.

Synonyms: EBN, BFNC, EBN1, NACHR, NACRA4, NACHRA4

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human CHRNA4

Gene Symbol: CHRNA4

Gene ID: 1137

Swiss prot: P43681

Calculated MW: 70kDa

Recommended dilution:
WB 1:200-1000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.