CHRNA4 Polyclonal Antibody

Background:
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.

Research Area: Cancer, Metabolism, Neuroscience

Synonyms:
A4 nicotinic receptor, Acetylcholine receptor alpha 4 neural, Acetylcholine receptor neuronal nicotinic alpha 4 subunit, ACH 4, ACH4, ACHA4, AChR, Acra 4, Acra4, Alpha4 nAChR, BFNC, Cholinergic receptor nicotinic alpha 4, Cholinergic receptor nicotinic alpha polypeptide 4, CHRNA 4, CHRNA4, EBN 1, EBN, EBN1, NACHR, NACRA 4, NACRA4, Neuronal acetylcholine receptor subunit alpha-4, Neuronal nicotinic acetylcholine receptor alpha 4 subunit

Immunogen: Recombinant protein of human CHRNA4

Swissprot: P43681
Gene Accession: BC096290

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1772/sc-5591